Bolardi

Saccharomyces Boulardii is indicated for the prevention and treatment of the following conditions:

• Diarrhea associated with antibiotic use
• Traveler's diarrhea
• Recurring intestinal disease caused by Clostridium difficile
• Side effects arising during treatment for Helicobacter pylori
• Symptoms of acute diarrhea, including diarrhea in infants
• Crohn's disease
• Ulcerative colitis and irritable bowel syndrome (IBS)

Dosing varies by indication

Antibiotic-associated diarrhea

250–500 mg taken orally two to four times daily.

Clostridium difficile-associated diarrhea (with antibiotics)

1 g daily for 4 weeks.

Crohn's disease

250 mg three times daily for up to 9 weeks, or 1 g daily alongside standard treatment.

Ulcerative colitis

250 mg three times daily.

Helicobacter pylori treatment support

500 mg twice daily in addition to standard H. pylori eradication therapy.

Capsules may be swallowed whole, or the contents may be mixed with food or dissolved in a liquid prior to administration, according to patient preference and ability to swallow.

Saccharomyces Boulardii is a non-pathogenic, transient probiotic yeast that acts as a temporary component of the intestinal flora. It survives gastric acid to colonize the gastrointestinal tract, where it helps re-establish healthy microflora and supports immunity and digestion.

Mechanism of action includes

• Anti-toxin activity: Saccharomyces Boulardii produces proteins that neutralize bacterial toxins, including those produced by Clostridium difficile.
• Anti-microbial action: It adheres to intestinal pathogens, reducing their adhesion to the intestinal wall and limiting their invasion of enterocytes.

Saccharomyces Boulardii is generally well tolerated when taken by mouth for up to 15 months.

• Common:
• Flatulence (gas)
• Bloating
• Constipation
• Rare but serious:
• Fungemia (fungal infection spreading into the bloodstream), particularly in critically ill or immunocompromised individuals
• Allergic reactions, which may include rash, itching, or swelling of the face, tongue, or throat

Saccharomyces Boulardii is contraindicated in

• Patients with a known allergy or hypersensitivity to yeast or any component of the formulation.
• Immunocompromised patients, due to the risk of fungemia (fungal infection spreading through the bloodstream).
• Patients with gastrointestinal wall perforation.

Yeast allergy

Patients with a documented yeast allergy should not use this product.

Immunocompromised patients

Critically ill individuals or those with a weakened immune system are at increased risk of developing fungemia. Use with caution or avoid in this population.

Children

Although Saccharomyces Boulardii is considered possibly safe for children when used appropriately, diarrhea in children should be evaluated by a healthcare professional before initiating treatment.

Concomitant antifungals

Avoid simultaneous use with antifungal medications, as these can reduce the effectiveness of Saccharomyces Boulardii.

Keep out of reach of children.

Immunocompromised patients

Use is contraindicated due to the risk of systemic fungal infection (fungemia).

Pediatric patients

Saccharomyces Boulardii is possibly safe for children when used appropriately. However, diarrhea in children should be assessed by a healthcare professional before starting treatment. Premature infants are at greater risk of adverse effects from probiotics; consult a healthcare provider before use in this group.

Renal or hepatic impairment

No specific data identified for dose adjustment in renal or hepatic impairment.

There is insufficient reliable information on the safety of Saccharomyces Boulardii during pregnancy or breastfeeding. It is not known whether it is excreted into breast milk. As a precaution, use during pregnancy and lactation should be avoided unless clearly indicated and discussed with a healthcare professional.

In case of accidental overdose, contact a Poison Control Center immediately or seek emergency medical assistance.

Antifungal medications (minor interaction): Concomitant use of antifungal agents — including fluconazole, terbinafine, and itraconazole — can reduce the effectiveness of Saccharomyces Boulardii. This interaction is classified as minor.

Patients should inform their healthcare provider of all medications, supplements, and herbal products they are taking.

What is the price of Bolardi 500 mg in Bangladesh (BD)?

Bolardi 500 mg price in Bangladesh is ৳16 per capsule. Prices may vary by pharmacy and are updated regularly on this page.

What is Bolardi used for?

Saccharomyces Boulardii is indicated for the prevention and treatment of the following conditions: - Diarrhea associated with antibiotic use - Traveler's diarrhea - Recurring intestinal disease caused by Clostridium…

Is Bolardi an antibiotic?

No, Bolardi is not an antibiotic.