Bolardi

Saccharomyces Boulardii is indicated for the prevention and treatment of the following conditions:

• Diarrhea associated with antibiotic use
• Traveler's diarrhea
• Recurring intestinal disease caused by Clostridium difficile
• Side effects of treatment for Helicobacter pylori infection
• Symptoms of acute diarrhea
• Diarrhea in infants
• Crohn's disease
• Ulcerative colitis and irritable bowel syndrome (IBS)

Antibiotic-associated diarrhea

250–500 mg taken two to four times daily.

Clostridium difficile-associated diarrhea

1 g daily for 4 weeks, taken alongside appropriate antibiotic therapy.

Crohn's disease

250 mg three times daily for up to 9 weeks, or 1 g daily in combination with standard therapy.

Helicobacter pylori infection (adjunct)

5 billion CFU daily alongside standard eradication treatment.

General use

The usual adult dose is 2 capsules once or twice daily, or as directed by a licensed medical practitioner.

Capsules may be taken in any of the following ways

• Swallowed whole with a full glass of water or other beverage.
• The capsule may be opened and the contents emptied directly onto the tongue, then swallowed with liquid.
• Contents may be sprinkled over semisolid food (e.g. yoghurt) and consumed immediately.
• Contents may be dissolved in a beverage and taken immediately.
• Take as directed by a licensed medical practitioner.

Saccharomyces Boulardii is a probiotic yeast that works by restoring and maintaining the natural balance of microorganisms in the gastrointestinal tract. It acts by inhibiting the adherence of pathogenic bacteria and yeast to the intestinal wall, thereby preventing their colonisation and growth. It also produces anti-inflammatory compounds that help reduce intestinal inflammation. By competing with harmful organisms for nutrients and attachment sites, it supports the recovery and integrity of the gut mucosal environment.

Saccharomyces Boulardii is generally well tolerated. The following adverse effects have been reported:

• Common:
• Gas and bloating (these typically subside as the body adjusts to the probiotic)
• Upset stomach
• Rare:
• Fungemia: fungal infection spreading through the bloodstream to the rest of the body. This has been reported rarely, primarily in patients with compromised immune systems or serious underlying illness.
• If any adverse effects occur, consult a physician immediately.

• Known hypersensitivity or allergy to Saccharomyces Boulardii, yeast, or any other ingredient in the formulation.
• Immunocompromised patients (e.g. those with HIV/AIDS, patients receiving immunosuppressive therapy, or critically ill patients) due to the risk of systemic fungal infection (fungemia).
• Patients with gastrointestinal wall perforation.

Immunocompromised and critically ill patients: There is a risk of developing systemic fungemia (a yeast infection that spreads through the bloodstream) in patients with weakened immune systems, those taking immunosuppressive medicines, or those who are critically ill. Use with caution and only under medical supervision in these populations.

Yeast allergy: Patients with a known allergy to yeast should be evaluated before use, as allergic reactions may occur.

Medical supervision: Patients who are taking other medications or who have underlying medical conditions should consult a healthcare professional before use.

Keep out of the reach of children.

Paediatric patients: Saccharomyces Boulardii is considered possibly safe in children when used appropriately and at recommended doses. A medical evaluation is recommended before use in infants and young children.

Immunocompromised patients: Use with caution. Critically ill patients and those with weakened immune systems are at increased risk of systemic fungemia and should only use this product under close medical supervision.

Elderly patients: No specific dose adjustment has been established; use as directed by a physician.

There is insufficient reliable information on the safety of Saccharomyces Boulardii during pregnancy or breastfeeding. As a precaution, use should be avoided during pregnancy and lactation unless expressly advised by a qualified healthcare professional.

Overdose may cause increased gas and constipation, which should resolve upon discontinuation or dose reduction. In the event of an overdose, seek immediate medical attention or contact a Poison Control Centre.

Antifungal medications: Systemic or oral antifungal agents — including fluconazole, terbinafine, and itraconazole — may reduce the effectiveness of Saccharomyces Boulardii by inhibiting the probiotic yeast. Concurrent use should be avoided where possible.

No other known severe, serious, moderate, or mild drug interactions have been identified.

Store at 20°–25°C (68°–77°F). Excursions permitted between 15°–30°C (59°–86°F). Refrigerate after opening. Do not freeze. Keep in a dry place, away from direct sunlight.

What is the price of Bolardi 250 mg in Bangladesh (BD)?

Bolardi 250 mg price in Bangladesh is ৳10 per capsule. Prices may vary by pharmacy and are updated regularly on this page.

What is Bolardi used for?

Saccharomyces Boulardii is indicated for the prevention and treatment of the following conditions: - Diarrhea associated with antibiotic use - Traveler's diarrhea - Recurring intestinal disease caused by Clostridium…

Is Bolardi an antibiotic?

No, Bolardi is not an antibiotic.