Femorose

Evening primrose oil is indicated for

• Premenstrual syndrome (PMS) symptoms
• Benign breast disease and cyclical mastalgia
• Support of lactation
• Atopic, allergic, and neurodermatitis
• Psoriasis
• Hypertension
• Rheumatoid arthritis
• Thrombosis
• Atopic eczema
• Dietary supplementation
• Promoting healthy skin, and nourishing brittle nails and hair

There is no universally established standard dose for evening primrose oil. Clinical studies have used doses ranging from 1 to 8 g per day in adults. A commonly used range in practice is 2 to 6 g per day, taken in divided doses.

Dose selection should be guided by the indication and a qualified healthcare provider, as optimal dosing has not been definitively established.

Take capsules orally, swallowed whole with water. It is advisable to take evening primrose oil capsules with food to minimise gastric discomfort. Do not exceed the recommended dose unless directed by a healthcare provider.

The principal active constituent of evening primrose oil is gamma-linolenic acid (GLA), an omega-6 essential fatty acid. GLA serves as a metabolic precursor to prostaglandins and other eicosanoids that play a central role in modulating inflammatory and immune responses. By supporting prostaglandin synthesis, evening primrose oil is thought to help regulate inflammation, strengthen the skin barrier, and influence platelet aggregation. The oil also exhibits antioxidant activity.

Evening primrose oil is generally well tolerated at recommended doses. Reported adverse effects are usually mild and transient, and include:

• Upset stomach
• Nausea
• Diarrhoea
• Headache

These effects have been observed at doses up to 6 g per day and typically resolve on discontinuation.

Evening primrose oil is contraindicated in

• Known hypersensitivity or allergy to evening primrose oil or any component of the capsule
• Seizure disorders or epilepsy
• Bleeding disorders
• Use alongside phenothiazine medicines in patients with schizophrenia (due to increased seizure risk)

• Discontinue use at least 2 weeks before any planned surgical procedure, as evening primrose oil may affect bleeding and anaesthetic management.
• Use with caution in patients with a history of seizure disorders.
• Use with caution in patients with known bleeding disorders or those taking anticoagulant or antiplatelet medicines.
• Avoid use near the end of pregnancy, as it may potentially delay labour.
• Consult a healthcare provider before use if you are pregnant, breastfeeding, or taking any prescription medicines.

Paediatric patients: Clinical trials have used doses of 2 to 4 g per day in children. Use in children should only be under medical supervision.

Patients scheduled for surgery: Discontinue evening primrose oil at least 2 weeks before any elective surgical procedure due to the potential risk of increased bleeding and interaction with anaesthetic agents.

Patients with epilepsy or seizure disorders: Evening primrose oil should be used with caution or avoided in this population due to the potential to lower the seizure threshold.

Pregnancy: Evening primrose oil is possibly safe when taken orally at doses up to 4 g per day for up to 10 weeks during pregnancy. However, it should be avoided near the end of pregnancy, as it may delay labour or affect uterine activity. Use during pregnancy should only be undertaken under the supervision of a healthcare provider.

Lactation: Safety during breastfeeding has not been fully established. Consult a healthcare provider before using evening primrose oil while breastfeeding.

Mild symptoms such as nausea, headache, or diarrhoea may occur with excessive intake. In the event of a suspected overdose, discontinue use and seek immediate medical attention or contact a Poison Control Centre. Do not combine different formulations of evening primrose oil simultaneously, as this increases the risk of overdose.

Evening primrose oil may interact with the following

Anticoagulants and antiplatelet agents (e.g., warfarin, aspirin, clopidogrel, NSAIDs): Evening primrose oil may enhance the blood-thinning effects of these medicines, increasing the risk of bleeding.

Phenothiazines (medicines used in schizophrenia): Concurrent use may increase the risk of seizures.

Anaesthetic agents: Use alongside general anaesthesia may increase seizure risk; evening primrose oil should be discontinued at least 2 weeks before scheduled surgery.

Lopinavir/ritonavir: Co-administration may increase plasma levels of these antiretroviral medicines.

CYP2C9 and CYP3A4 substrates: Evening primrose oil may affect the metabolism of drugs processed through these cytochrome P450 enzymes, potentially altering their efficacy or side-effect profile.

Store at room temperature (below 30°C), away from moisture and direct heat. Keep out of reach of children.

What is the price of Femorose 1000 mg in Bangladesh (BD)?

Femorose 1000 mg price in Bangladesh is ৳12 per capsule. Prices may vary by pharmacy and are updated regularly on this page.

What is Femorose used for?

Evening primrose oil is indicated for: - Premenstrual syndrome (PMS) symptoms - Benign breast disease and cyclical mastalgia - Support of lactation - Atopic, allergic, and neurodermatitis - Psoriasis - Hypertension -…

Is Femorose an antibiotic?

No, Femorose is not an antibiotic.