Epam

Epam is indicated in disturbances of sleep of various aetiology, insomnia of the neurotics, involutional restlessness, disturbances of sleep of cerebrosclerotic patients, Myoclonic seizures etc.

Treatment of insomnia is usually initiated with a dose of 5 mg at night although 2.5 mg is appropriate in elderly patient. The dose may be increased to 10 mg at night if insomnia is severe.

Myoclonic seizures: Children: (up to 30 kg of body weight) between 0.3 and 1.0 mg/kg/day given in 3 divided doses. Treatment should be initiated with lower dose than the usual recommended dosage range in order to determine tolerance and response.

Dosage should be individualized for maximal beneficial effect.

Nitrazepam is a benzodiazepine derivative nearly related to diazepam. Contrary to barbiturate derivatives Nitrazepam gives free way to physiologic sleep by increasing the stimulus threshold of hypocampus and does not inhibit cortical function. After a sleep with Nitrazepam patients awaken thoroughly relaxed.

Patients do not show additional symptoms even after a prolonged treatment.

It is not recommended to use Nitrazepam during the first three months of the pregnancy. In myasthenia gravis, administration of Nitrazepam is contra-indicated.

To be dispensed only by or on the prescription of a registered physician. To be taken as directed by physician. Keep out of reach of children. Keep in a cool & dry place.

Symptoms

Somnolence, drowsiness, confusion, ataxia, impaired reflexes, coma, dyspnoea, hypotension, respiratory and cardiovascular depression.

Management

Supportive. Gastric lavage may be beneficial if performed soon after ingestion. Flumazenil may reverse benzodiazepine-induced CNS depression.

CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.

Store at room temperature. Protect from light and moisture.

What is the price of Epam 5 mg in Bangladesh (BD)?

Epam 5 mg price in Bangladesh is ৳0.75 per tablet (৳300 per strip). Prices may vary by pharmacy and are updated regularly on this page.

What is Epam used for?

Epam is indicated in disturbances of sleep of various aetiology, insomnia of the neurotics, involutional restlessness, disturbances of sleep of cerebrosclerotic patients, Myoclonic seizures etc.

Is Epam an antibiotic?

No, Epam is not an antibiotic.