Dolonac

Extended release tablet : The recommended dose in adults is one 200 mg Aceclofenac tablet daily or as prescribed by the physician. Film coated tablet : The recommended dose in adults is 100 mg, twice daily.

Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.

Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.

Aceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.

Caution should be exercised to patients with active or suspected peptic ulcer or gastro-intestinal bleeding moderate to severe hepatic impairment and cardiac or renal impairment. Caution should also be exercised in patients suffering from dizziness or urticaria.

No significant drug interactions has not been observed but close monitoring of patients is required when it is used with: Lithium and Digoxin : may increase plasma concentration of lithium and digoxin. Diuretics : may interact the activity of diuretics. Anticoagulants : may enhance the activity of anticoagulant. Methotrexate : may increase the plasma level of methotrexate.