Clotrim

One suppository should be inserted intravaginally daily (preferably at night) for three consecutive days. The suppository should be inserted into the vagina, as high as possible. This is best achieved when lying back with legs bent up. Or as directed by the physicians.

Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, moulds and bacteroids. Clotrimazole is also active against certain gram-positive bacteria especially Staphylococci and Tricomonas. Like other imidazoles, Clotrimazole alters the permeability of fungal cell walls by interfering with cell wall lipids. At fungi static levels the main effect is inhibition of ergosterol synthesis but at higher concentrations there is an additional mechanism of membrane damage unrelated to sterol synthesis.

Occasional skin irritation or burning sensation may occur in a very few cases which are not considered harmful.

Clotrimazole is contraindicated for patients who are hypersensitive to Clotrimazole.

Constituents of the vaginal suppository may be incompatible with rubber in both contraceptive condoms and diaphragms. During period this treatment won't have good result. Avoid oral or ophthalmic use.