Calcium carbonate reacts with gastric acid to produce a salt and water. For calcium carbonate the postulated chemical reaction is: CaCO3
+2HCl = CaCl2
+H2
O+CO2. Two grams of calcium carbonate will readily bring 100 ml of hydrochloric acid to a pH above 6. The increase in gastric pH diminishes the activity of pepsin in the gastric secretion. Up to 30% of the oral calcium load may be absorbed.
Orally administered Carbocal may be irritating to the GI tract. It may also cause constipation. Hypercalcaemia is rarely produced by administration of calcium alone, but may occur when large doses are given to patients with chronic renal failure.
When hypercalcaemia occurs, discontinuation of the drug is usually sufficient to return serum calcium concentrations to normal. Calcium salts should be used cautiously in patients with sarcoidosis, renal or cardiac disease, and in patients receiving cardiac glycosides.
Use in children: Carbocal has been extensively studied in children and infants with chronic renal failure and is both safe and effective.
Use in elderly: In case of elderly patients with renal failure when Carbocal is taken constipation may be troublesome one for this group. For this reason, monitoring of serum calcium and phosphate is of course indicated for elderly patients.
Calcium containing drugs have been widely used in pregnancy by way of oral calcium supplementation or antacid therapy. Calcium Carbonate can be used in lactating women too.
Carbocal may enhance the cardiac effects of digoxin and other cardiac glycosides, if systemic hypercalcaemia occurs. Carbocal may interfere with the absorption of concomitantly administered tetracycline preparations and in chronic renal failure modification of vitamin D therapy may be required to avoid hypercalcaemia when Carbocal is used as the primary phosphate binder.
Store in a cool, dry place in controlled room temperature.
Carbocal 500 mg price in Bangladesh is ৳2.2 per tablet (৳220 per strip). Prices may vary by pharmacy and are updated regularly on this page.
250 mg or 500 mg tablet : Elemental Carbocal tablet is used for the treatment or prevention of calcium depletion in patients in whom dietary measures are inadequate. Conditions that may be associated with calcium…
No, Carbocal is not an antibiotic.
Always consult a registered physician before taking any medicine. Prices shown are MRP and may vary by pharmacy.
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