Atofix

Atofix ointment is used topically to treat atopic dermatitis, commonly known as eczema.

The usual adult dosage is an appropriate amount of the Difamilast 1% ointment applied to the affected area twice daily. The usual pediatric dosage is an appropriate amount of the Difamilast 0.3% ointment applied to the affected area twice daily.

Difamilast is a phosphodiesterase 4 (PDE4) inhibitor. It increases cyclic adenosine 3',5'-monophosphate (cAMP) concentration and consequently suppresses the production of inflammatory cytokines, exerting effects in treatment of atopic dermatitis.

Well tolerated in recommended dosage. At higher dosage it may cause mild skin reactions at the site of application, such as redness, burning, or stinging.

Difamilast is contraindicated in individuals with a known hypersensitivity to the drug.

External use only. Atofix ointment is not for oral, ophthalmic, or intravaginal use.

If there is any hypersensitivity issue with the use of Atofix, treatment should be discontinued.

Difamilast is not recommended for pregnant women or women who may possibly be pregnant. For breastfeeding, safety profile has not been fully established.

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.