Alkalina is indicated in-
Sodium bicarbonate is a systemic alkalizer, which increases plasma bicarbonate, buffers excess hydrogen ion concentration, and raises blood pH, thereby reversing the clinical manifestations of acidosis. It is also a urinary alkalizer, increasing the excretion of free bicarbonate ions in the urine, thus effectively raising the urinary pH. It also replenishes electrolyte imbalance in severe diarrhea where the loss of bicarbonate can be significant.
Oral : The usual dose is 300 mg to 2 grams, 1 to 4 times daily. Intravenous (Severe metabolic acidosis): Adult: By slow inj of a hypertonic solution of up to 8.4% (1000 mmol/L), or by continuous infusion of a weaker solution, usually 1.26% (150 mmol/L). For correction of acidosis during advanced cardiac life support procedures, 50 ml of an 8.4% solution may be given. Elderly: Dosage adjustments may be required.
Common side effects: Headache Nausea Irritability Notify your doctor you develop any of the following effects: Muscle weakness Slow reflexes Confusion Swelling of the feet or ankles Black tar-like stools Coffee-ground vomit
Always consult a registered doctor before taking any medicine. This information is for general knowledge only.
This drug is contraindicated in hypersensitivity hypoventilatory states, excessive chloride depletion owing to continuous gastric fluid loss from vomiting or GI suctioning, metabolic and/or respiratory alkalosis, hypocalcemia and diuretics known to produce hypochloremic alkalosis.
Some drugs that may interact with Alkalina are : Aspirin and other salicylates, memantine, medications with enteric coating. Potentially hazardous interactions with Corticosteroids and Corticotropin, Alkalis, Calcium, Diuretics and Potassium. It can decrease the effectiveness of certain drugs including Ampicillin, Atazanavir, Ketoconazole, Itraconazole, Iron supplements, Sucralfate etc.
Caution should be taken for patients with pre-existing heart disease, kidney disease, liver disease, high blood pressure, any allergies because this medication contains salt (sodium), do not use it if you are on a salt restricted diet.