Nesudil ophthalmic solution is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Netarsudil is a Rho kinase inhibitor, works at the cellular level within the trabecular outflow pathway to relax actin-myosin. This causes relaxation within the trabecular meshwork and the inner wall of Schlemm's canal and decreases episcleral venous pressure (EVP).
The recommended dosage is one drop in the affected eye(s) once daily in the evening. Pediatric Use : Safety and effectiveness in pediatric patients below the age of 18 years have not been established. Use in elderly patients : No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
The most common ocular adverse reaction observed in controlled clinical studies with Nesudil was conjunctival hyperemia, corneal verticillata, instillation site pain, corneal staining and blurred vision.
This eye drops is contraindicated in patients who are hypersensitive to any component of this preparation.
Always consult a registered doctor before taking any medicine. This information is for general knowledge only.
For ophthalmic use only. To avoid possible contamination of the drops, do not touch the dropper tip or to any surface. Nesudil can be used with other topical eye drug products, but they should be administered at least 5 minutes apart from each other. Contact lenses should be removed prior to instillation of Nesudil and may be reinserted 15 minutes following its administration.