Neomycin Sulphate + Polymyxin B Sulphate + Pramoxine

This is a first aid cream. It prevents infections and provides temporary relief of pain or discomfort in minor cuts, scrapes and burns.

This cream is a combination of Neomycin, Polymyxin B and Pramoxine HCl. Neomycin is bactericidal for many gram-positive and gram-negative organisms. It is an aminoglycoside antibiotic that inhibits protein synthesis by binding with ribosomal RNA and causing misreading of the bacterial genetic code. Polymyxin B is bactericidal for a variety of gram-negative organisms. It increases the permeability of the bacterial cell membrane by interacting with the phospholipids components of the membrane. Pramoxine is an external analgesic that provides temporary relief of pain or discomfort.

Clean the affected area. Apply a small amount of product (an amount equal to the surface area of the tip of a finger). May be covered with a sterile bandage. Safety and effectiveness in children below 2 years of age have not been established.

Topical antibiotics, particularly Neomycin sulphate, may cause cutaneous sensitization. The manifestations of sensitization to topical antibiotics are usually itching and reddening. When used in small doses, no common side effects have been reported with Nuprin.