Naftidrofuryl Oxalate

Azelto capsule is used to treat peripheral vascular disorders (blood circulation problems outside the brain and heart). It is used to treat the following symptoms of these disorders: Intermittent claudication Cramps in legs at night Severe pain in legs while resting (rest pain) ... Read more Azelto capsule is used to treat peripheral vascular disorders (blood circulation problems outside the brain and heart). It is used to treat the following symptoms of these disorders: Intermittent claudication Cramps in legs at night Severe pain in legs while resting (rest pain) Pale or blue fngers or toes which get worse when it is cold Numbness, tingling or burning feelings in fngers or toes (Raynaud’s syndrome or acrocyanosis) Open sores on the legs or feet (trophic ulcers) Poor circulation caused by diabetes (diabetic arteriopathy) To treat gangrene

Naftidrofuryl oxalate possesses a 5HT2-blocking activity and counteracts both the vasoconstrictor effect and the effect promoting platelet aggregation due to serotonin. Naftidrofuryl oxalate has a direct effect on intracellular metabolism. Thus it increases ATP level, decreases lactic acid level in ischemic conditions and enhances the cellular oxidative capacity. Also, Naftidrofuryl oxalate is a powerful spasmolytic agent.

One or two Naftidrofuryl oxalate capsules three times daily during meals for a minimum of three months or at the discretion of the physician.

Gastrointestinal disorders (uncommon): Diarrhoea, nausea, vomiting and epigastric pain. Renal and urinary disorders (very rare): Calcium oxalate kidney stones. Skin and subcutaneous tissue disorders (uncommon): Skin rash. Hepatobiliary disorders (rare): Liver damage.