Anacaine HC ano-rectal cream is used for the anti-inflammatory and anesthetic relief form itching, pain, soreness and discomfort due to hemorrhoids, anal fissures, anal pruritus and similar conditions of the anal area.
Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency. Lidocaine is an amide type local anesthesia. It stabilises the neuronal membrane and inhibits Na ion movements, which are necessary for conduction of impulses. In the heart, lidocaine reduces depolarisation of the ventricles during diastole and automaticity in the His-Purkinje system. Duration of action potential and effective refractory period are also reduced.
This cream should be applied to the affected area(s) twice daily or as directed by physician. Applicator tip should be gently inserted into the anal area (areas of discomfort and anal opening). Applicator and tube should not completely insert in the anus or rectum. Pediatric Use: Safety and efficacy in pediatric patients have not been established.
During or immediately following application of Anacaine Cream, there may be transient stinging or burning from open areas of skin, or transient blanching (lightening), or erythema (redness) of the skin.
Always consult a registered doctor before taking any medicine. This information is for general knowledge only.
Patients with a history of hypersensitivity to any of its ingredients.
This cream should be used with caution in patients receiving antiarrhythmic drugs of Class I (e.g., disopyramide, procainamide, quinidine etc), other corticosteroids/immunosuppressant drugs (e.g., cyclosporine, prednisone etc).
If infection occurs, the drug should be discontinued. Systemic absorption may occur when extensive areas are treated and may cause suppression of hypothalamic-pituitary-adrenal (HPA) axis; avoid using for prolonged periods or with occlusive dressings. Caution should be used with impaired hepatic function and patients taking class I antiarrhythmics.