Axidin is indicated in- Gastric ulcer Duodenal ulcer Anastomotic ulcer Acute stress ulcer Reflux esophagitis and Zollinger-Ellison syndrome. Axidin is also indicated for the treatment of acute gastritis, chronic gastritis in the acute exacerbation stage.
Famotidine is a histamine H2-receptor antagonist. Famotidine completely inhibits the action of histamine on H2- receptors of parietal cell. It inhibits basal, overnight and pentagastrin stimulated gastric acid secretion. The H2- receptor antagonist activity of Famotidine is slowly reversible, since the drug dissociates slowly from H2-receptor.
Tablet: For gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastro-intestinal hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome : Usual dose for adults: Famotidine 20 mg twice daily (after breakfast and after supper or before bed time) or Famotidine 40 mg can be administered orally once daily at bed time. For the treatment of acute gastritis, chronic gastritis in acute exacerbation stage : Usual dosage for adults is Famotidine 20 mg orally twice a day (after breakfast and after supper or before bed time). Also Famotidine 40 mg can be orally administered once a day (before bed time), dosage should be adjusted according to age and symptoms. Most ulcer patients heal within 4-8 weeks. For maintenance therapy the recommended oral dose is 20 mg once daily. Or, as directed by the registered physician. Powder for Suspension: Gastroesophageal Reflux Disease(GERD) : <1 year of age: 0.5 mg/kg/dose of famotidine oral suspension up to 8 weeks once daily in patients Age 3 to 11 months: 0.5 mg/kg/dose twice daily up to 8 weeks Age 1 to 2 months: 0.5 mg/kg/dose once daily up to 8 weeks Neonates: 0.5 mg/kg/dose maximum once daily up to 8 weeks Patients 1-16 years of age: Gastroesophageal Reflux Disease(GERD): 1 mg/kg/day p.o. divided b.i.d. up to 40 mg b.i.d. Duodonal ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day. Peptic ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day. Maintenance therapy: 40 mg at daily night. Reflux esophagitis: 2 mg/kg/day Zollinger-Ellison Syndrome: 40 mg 3 times daily.
Always consult a registered doctor before taking any medicine. This information is for general knowledge only.
Eruption, constipation, diarrhoea, dry mouth, nausea, vomiting, tachycardia, high blood pressure, headache, drowsiness or insomnia may rarely occur.
Known hypersensitivity to any component of the drug.
No clinically important drug interactions have been identified. Axidin does not interact with the cytochrome P450-linked drug-metabolizing enzyme system.
The drug should be used in the minimum required amount depending upon the conditions of the diseases. The drug should be administered carefully with elderly patients, patients with renal failure and hepatic disorders.