Dicycloverine Hydrochloride

Abdorin is indicated in: Functional bowel/irritable bowel syndrome Urinary incontinence secondary to unstable detrusor muscle Infantile colic GIT spasm Colicky abdominal pain Diverticulitis Abdominal colic

Dicycloverine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract. Dicycloverine HCl Injection is a sterile, pyrogen-free, aqueous solution for intramuscular injection (Not For Intravenous Use). It works at specific receptors, called cholinergic (or muscarinic) receptors, located on the involuntary muscle in the walls of the gut. By binding to these receptors dicycloverine prevents certain chemicals produced by the body from interacting with these receptors. This causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm.

For oral dosage forms: Adults :10 to 20 mg three times a day. Children over 6 months of age : 5 to 10 mg three times a day. For injectable dosage form: Adults : Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be used for periods longer than 1 or 2 days. Children : Dose must be determined by the doctor.